A Futuristic Review on Advances and Potential Applications of Herbal Plant Product-Based Drug Delivery Systems for Psoriasis

Abstract

Psoriasis is a skin problem that just will not go away. It is caused by the system not working like it should. This makes the skin cells turn over fast and causes a lot of inflammation. Doctors usually treat psoriasis with things like corticosteroids, retinoids and biologic agents. These treatments can have bad side effects are expensive and people often do not take them like they are supposed to. Because of this people are looking into medicines for psoriasis. Herbal medicines are often seen as safer and cheaper. They also have properties that can help reduce inflammation and make the immune system work better. Psoriasis treatments need to be safe and work well that is why people are looking into medicines, for psoriasis. When we use plants to make medicine in the way the good stuff from the plants does not dissolve well in water it does not go through the skin easily and it breaks down quickly. This means that the medicine does not work well as it should. To make the medicine work better for people with psoriasis scientists are creating ways to deliver the medicine. They are trying different ways to do this including things, like phytosomes, liposomes, nanoemulsions, solid lipid nanoparticles, hydrogels, polymeric micelles and other special systems that can carry the herbal agents to where they are needed. These new systems can protect the things in plants help them get into the skin of people with psoriasis and release them in a way that we can control. This means they can get more of the drug to where it's needed keep it there for longer and maybe even reduce the bad side effects that happen when we take drugs by mouth or put them on our skin. So using remedies with these new delivery systems could be a great addition to the usual way of treating people or even a different way of treating people altogether. This could make people feel better reduce the risks and make patients happier, with their treatment. Herbal remedies and these new systems could really work well together to make people feel better. Future work should prioritize well designed clinical trials, robust standardization of herbal formulations and scalable manufacturing strategies to firmly establish herbal based delivery systems as reliable treatment options for psoriasis.