Medicinal Uses and Therapeutic Potential of Safed Musli (Chlorophytum borivilianum): A Review

Abstract

Safed Musli (Chlorophytum borivilianum) is an important Indian medicinal plant traditionally used to promote vitality, reproductive health and recovery from weakness. Its tuberous roots contain steroidal saponins, polysaccharides, fructans, and other phytoconstituents that have attracted interest in pharmaceutical and nutraceutical research. This review paper critically examines its botanical identity, ethnomedicinal applications, phytochemical composition, pharmacological activities, clinical evidence, safety, standardization and conservation. Evidence for consistent testosterone enhancement and therapeutic benefits in diabetes, cancer, and inflammatory disorders remains insufficient. Variations in botanical authentication, extraction methods, chemical composition and dosage can alter the effect of the medicinal potencial. Sustainable cultivation and conservation of genetic diversity are also essential for reliable sourcing. Overall, C. borivilianum represents a promising candidate for focused therapeutic investigation, but its clinical applications require stronger and reproducible evidence.